FBI informant William O'Neal (LaKeith Stanfield) infiltrates the Illinois Black Panther Party and is tasked with keeping tabs on their charismatic leader, Chairman Fred Hampton (Daneil Kaluuyah). A career thief, O'Neal revels in the danger of manipulating both his comrades and his handler, Special Agent Roy Mitchell (Jesse Plemons). Hampton's political prowess grows just as he's falling in love with fellow revolutionary Deborah Johnson (Dominique Fishback). Meanwhile, battle wages for O'Neal's soul. Will he align with the forces of good? Or subdue Hampton and The Panthers by any means, as FBI Director J. Edgar Hoover commands?